In brief about disease. Autoimmunnyj (or limfotsitarnyj) tireoidit (its other name - illness Hasimoto or as still speak - Hashimoto) develops in that case when in whey of blood of the person appear autoantitela to a thyroid gland when in a thyroid gland fabric there are antibodies. In patogeneze (i.e. pathological development of illness Hasimoto much in common with diffuznym a toxic craw. Both these diseases are connected with presence of specific defect immunologicheskoj the organism protection which essence is reduced to occurrence of self-jet or so-called "forbidden" clones timuszavisimyh limfotsitov - T-limfotsitov. In a healthy organism the system supressorov suppresses activity T-limfotsitov and excludes their interaction with komplementarnymi thyroid gland antigenes. And here at autoimmunnom tireoidite defect of this system (most likely the genetic plan) is formed and, as consequence, is broken immunologicheskaja tolerance (stability) and, "forbidden" clones T-limfotsitov start to co-operate with komplementarnymi antigenes of cages of a thyroid gland. On what appears local kletochnooposredovannyj the immune answer. T-limfotsity co-operate with V-limfotsitami with the subsequent transformation of the last in plasmatic cages which in turn form poliklonalnye autoantitela to own thyroid gland. And they render on cages of follicles (t.e.strukturnyh eelementov) a thyroid gland destroying action. In whey of blood of patients autoimmunnym tireoiditom are constantly found out autoantitela to tireoglobulinu, to components kolloida a thyroid gland, to microcatfishes of ferruterous cages, to tiroksinu and trijodtironinu, to receptors tireotropnogo a hypophysis hormone on membranes tireotsitov. As the starting mechanism any stressful situation can serve in disease development for an organism - operation, a sharp inflammation of a thyroid gland, application of the radioactive isotopes, inadequate treatment by preparations of iodine, etc. Progressing autoimmunnogo process leads to destructive changes in a thyroid gland and development gipotireoza, that is in turn connected: with infringement of biosynthesis of hormones of a thyroid gland as a result of it limfotsitarnoj infiltratsii, destruction tireoidnoj fabrics, with presence of antibodies which block linkage tireotropnogo a hormone with receptors and with some other processes. And gipertireoz (hyperfunction) sometimes develops at autoimmunnom tireoidite. That is caused by synthesis of the antibodies stimulating proliferatsiju and hyperfunction tireotsitov (thyroid gland cages). gipertireoz, arising at the very beginning of disease, it is connected with destruction of follicles of a thyroid gland and considerable quantity emission tiroksina and trijodtironina in blood. Treatment at this disease should be directed on elimination of deficiency of own hormones of a thyroid gland and activity reduction autoimmunnyh processes in a thyroid gland. It is necessary and it is possible to carry out only under the vigilant control of the doctor-endokrinologa (especially at children and teenagers!!!). Any attempt to do without the doctor-endokrinologa results (I underline - cannot result, and results always!!!) To the hardest consequences. Quite often - irreparable.

In brief about disease of your child. Autoimmunnyj (or limfotsitarnyj) tireoidit (its other name - illness Hasimoto or as still speak - Hashimoto) develops in that case when in whey of blood of the person appear autoantitela to a thyroid gland when in a thyroid gland fabric there are antibodies. In patogeneze (i.e. pathological development of illness Hasimoto much in common with diffuznym a toxic craw. Both these diseases are connected with presence of specific defect immunologicheskoj the organism protection which essence is reduced to occurrence of self-jet or so-called "forbidden" clones timuszavisimyh limfotsitov - T-limfotsitov. In a healthy organism the system supressorov suppresses activity T-limfotsitov and excludes their interaction with komplementarnymi thyroid gland antigenes. And here at autoimmunnom tireoidite defect of this system (most likely the genetic plan) is formed and, as consequence, is broken immunologicheskaja tolerance (stability) and, "forbidden" clones T-limfotsitov start to co-operate with komplementarnymi antigenes of cages of a thyroid gland. On what appears local kletochnooposredovannyj the immune answer. T-limfotsity co-operate with V-limfotsitami with the subsequent transformation of the last in plasmatic cages which in turn form poliklonalnye autoantitela to own thyroid gland. And they render on cages of follicles (t.e.strukturnyh eelementov) a thyroid gland destroying action. In whey of blood of patients autoimmunnym tireoiditom are constantly found out autoantitela to tireoglobulinu, to components kolloida a thyroid gland, to microcatfishes of ferruterous cages, to tiroksinu and trijodtironinu, to receptors tireotropnogo a hypophysis hormone on membranes tireotsitov. As the starting mechanism any stressful situation can serve in disease development for an organism - operation, a sharp inflammation of a thyroid gland, application of the radioactive isotopes, inadequate treatment by preparations of iodine, etc. Progressing autoimmunnogo process leads to destructive changes in a thyroid gland and development gipotireoza, that is in turn connected: with infringement of biosynthesis of hormones of a thyroid gland as a result of it limfotsitarnoj infiltratsii, destruction tireoidnoj fabrics, with presence of antibodies which block linkage tireotropnogo a hormone with receptors and with some other processes. And gipertireoz (hyperfunction) sometimes develops at autoimmunnom tireoidite. That is caused by synthesis of the antibodies stimulating proliferatsiju and hyperfunction tireotsitov (thyroid gland cages). gipertireoz, arising at the very beginning of disease, it is connected with destruction of follicles of a thyroid gland and considerable quantity emission tiroksina and trijodtironina in blood. Treatment at this disease should be directed on elimination of deficiency of own hormones of a thyroid gland and activity reduction autoimmunnyh processes in a thyroid gland. It is necessary and it is possible to carry out only under the vigilant control of the doctor-endokrinologa (especially at children and teenagers!!!). Any attempt to do without the doctor-endokrinologa results (I underline - cannot result, and results always!!!) To the hardest consequences. Quite often - irreparable. Thyroid gland hormones is one, hormones of parathyroid glands is another, hormones of adrenal glands is absolutely already the third. Hormones to hormones rozn.

the Source: the Internet edition "a health Planet" № December, 10th 2003 on Open Company "MediaRoom" site www.ph.ru